AI-Powered Brain Aneurysm Detection and Assessment on CT Angiography
Most brain aneurysms stay silent until they rupture, and many are found by chance. UPTUNITY™ | Aneurysm helps radiologists spot them on the head CTA in front of them, then track every change from one scan to the next.
Silent for Years. Fatal in Minutes.
1 in 50 adults in the United States lives with an unruptured brain aneurysm¹. For years it causes no symptoms. Then, without warning, the wall gives way. Blood floods the space around the brain, the patient describes the worst headache of their life, and in about half of cases the rupture is fatal¹. Many can already be seen long before, on a scan ordered for something else.
Every 18 minutes in the United States, a brain aneurysm ruptures
About 15% of patients die before reaching the hospital, and around two thirds of survivors live with a lasting neurological deficit¹. Once it ruptures, the window has closed.
The aneurysm is already on the screen
A CTA for a stroke workup. A trauma. A headache. The radiologist reads for the question asked, and a small aneurysm can sit in plain view without making it into the report. Even once it is reported, the story is not over: an aneurysm that grows is one that can rupture, so it has to be measured again, scan after scan.
UPTUNITY™ | Aneurysm turns that moment into a finding. It flags each suspected aneurysm on the CTA already acquired, with its vessel, side and size. Then it measures it again at every follow-up scan, so a growing aneurysm is on the radiologist’s screen before it ruptures.
¹ Brain Aneurysm Foundation, Statistics and Facts.
Brain Aneurysm Detection and Assessment
Detection and first-line assessment: it flags each suspected saccular brain aneurysm greater than 3 mm on head CTA, with its location and size, so each suspected aneurysm is brought to the radiologist’s attention during the read.
Source: standalone study, 423 cases, 4 CT vendors; reader study, 8 readers, 230 cases. *Application processing time; overall delivery depends on vendor, network and equipment.
Advanced quantification and follow-up: it measures a known aneurysm on head CTA in 3D and compares it with the prior scan, to show whether it is changing.
Source: validation on 236 aneurysms; volume agreement R = 0.93 vs ground truth.
Detection Coverage
Your questions, answered
What is the difference between UPTUNITY™ | Aneurysm Detection and UPTUNITY™ | Aneurysm Management?
UPTUNITY™ | Aneurysm Detection detects, localizes and measures each aneurysm: on a single head CTA, it flags each saccular aneurysm greater than 3 mm, labels the parent vessel and gives its maximum diameter in 3 planes. UPTUNITY™ | Aneurysm Management adds advanced 3D measurements (volume, dome height, neck width, aspect ratio) and follow-up, with an automated comparison between two exams. Two offers: UPTUNITY™ | Aneurysm Detection on its own, or UPTUNITY™ | Aneurysm with both modules. UPTUNITY™ | Aneurysm Management is always used together with UPTUNITY™ | Aneurysm Detection.
Can UPTUNITY™ | Aneurysm Detection be deployed on its own?
Yes. UPTUNITY™ | Aneurysm Detection can be deployed on its own, or together with UPTUNITY™ | Aneurysm Management in UPTUNITY™ | Aneurysm, the bundle with both modules. UPTUNITY™ | Aneurysm Management is always deployed together with UPTUNITY™ | Aneurysm Detection.
Will it work with our existing PACS?
Yes. It integrates into your existing imaging platform through Avicenna.AI partnerships, or runs on the AVI platform: it uses the CT series already in PACS and sends the results back to PACS, with no separate viewer. Already running CINA tools? It extends the same integration, with no new procurement or security review cycle. FDA-cleared, available in the United States; not CE-marked.
Why greater than 3 mm?
Because that is where detection is both reliable and clinically meaningful. To be characterized with confidence, an aneurysm must be visible on at least two contiguous slices. With a maximum supported slice thickness of 1.25 mm, two slices cover 2.5 mm, so 3 mm is the smallest size that keeps an aneurysm on at least two slices across all supported acquisitions, with a margin for partial-volume effects. Below 3 mm, that visibility becomes inconsistent and false positives rise. It is also where the risk profile changes: small unruptured saccular aneurysms carry a very low rupture risk, and guidelines generally recommend surveillance at that size.
- For complete operating instructions, warnings, precautions and other important safety information, refer to the Instructions for Use.
- Manufacturer: Avicenna.AI (France).
- Medical devices Class II under the Code of Federal Regulations of the United States of America 21CFR on Medical Devices, FDA 510(k) K262062 and K262147. Not CE-marked, not available outside the United States.
- UPTUNITY is a trademark of Bracco Imaging S.p.A.
