CINA-PE AI-Powered Pulmonary Embolism Detection on Chest CT Angiography
The patient arrived at the ER with acute chest pain and shortness of breath. A dedicated CT pulmonary angiogram (CTPA) has been acquired. The clinical question is open, and the PERT team is standing by. In a standard worklist, the scan waits. CINA-PE moves it to the front, delivering a notification to the radiologist within a mean of one minute of acquisition.
The Worklist Does Not Know the Urgency.
A dedicated CTPA for suspected PE is not a routine scan. It is the answer to a clinical question that is already open. The worklist does not sort by urgency.
Massive pulmonary embolism
When the patient is hemodynamically unstable, the scan result determines whether the PERT team prepares or waits. A suspected PE sitting undifferentiated in a queue is time the clinical team is not acting. CINA-PE flags the case and delivers a notification before it would normally be opened.
Stable pulmonary embolism
Hemodynamically stable does not mean low risk. Clot extension, right heart strain, and deterioration are real consequences of a result that arrives late. With CINA-PE, every suspected positive is flagged immediately, at any hour and at any volume.
Every dedicated chest CT angiography is analyzed automatically. When PE is suspected, the radiologist receives an alert with preview slices showing the suspected location, before the clinical team is kept waiting. No manual trigger. No change to the existing workflow.
Pulmonary Embolism Detection
Triage and notification tool for dedicated chest CT angiography in symptomatic adults with suspected pulmonary embolism, supporting radiologist workflow prioritization in emergency and hospital settings.
Source: FDA 510(k) standalone performance study (2021), slice thickness ≤ 2.5 mm.
Triage and notification tool for dedicated chest CT angiography in symptomatic adults with suspected pulmonary embolism, supporting radiologist workflow prioritization in emergency and hospital settings.
Source: clinical evaluation report under the EU Medical Device Regulation (MDR 2017/745), slice thickness ≤ 2.5 mm.
Detection Coverage
Backed by peer-reviewed studies
Peer-reviewed studies validating CINA-PE performance.
Four-hospital US health system: time-to-consult and in-hospital mortality measured before and after CINA-PE.
High-volume tertiary center: effect of earlier notification on anticoagulation and PERT team mobilization.
Hôpital Foch reader study: how CINA-PE changes residents’ performance and agreement on after-hours CTPAs.
94% sensitivity and 95% specificity on CTPA, recovering 76% of the cases missed on initial clinical reports.
Figures as reported by each study.
A Customer’s Perspective
“In addition of being a high-performance software, Avicenna.AI gives access to patient results usually within 2 to 5 minutes, thus allowing radiologists to accelerate time of interpretation, providing a better service for our hospitals and better patient outcomes.”
Your questions, answered
What does CINA-PE detect, and who is it designed for?
CINA-PE is a triage and notification tool for dedicated chest CT angiography in symptomatic adults with suspected pulmonary embolism. It analyzes every CTPA automatically, delivers a notification to the radiologist’s worklist if a suspected PE is identified, and provides a preview of up to five flagged slices. It is not designed for contrast-enhanced CT scans acquired for other clinical reasons.
How does CINA-PE reduce the time between scan and clinical action?
In a standard worklist, a suspected PE case waits behind routine studies while the clinical team waits for a result. CINA-PE delivers a notification within a mean of one minute of scan acquisition, before the case would normally be reached. In the Shapiro et al. study at a four-hospital US health system, time-to-consult dropped from 240 minutes to under 7 minutes following implementation.
What is the difference between CINA-PE and CINA-iPE?
CINA-PE analyzes dedicated CT pulmonary angiography in symptomatic patients referred specifically for suspected PE, using a high-contrast pulmonary timing protocol. CINA-iPE analyzes contrast-enhanced CT scans acquired for entirely different reasons, such as oncology staging or trauma, where PE was not suspected. They are different tools, different algorithms, and different clinical workflows.
- Instructions for Use are available.
- Manufacturer: Avicenna.AI (France).
- Medical device Class IIb following the European Regulation on Medical Device (EU) 2017/745.
- Medical device Class II following the Code of Federal Regulations of the United States of America 21CFR on Medical Devices.
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