CINA-LVO

AI-Powered Large Vessel Occlusion Detection on CT

Large vessel occlusion is responsible for the most severe ischemic strokes. CINA-LVO analyzes brain CT angiography scans automatically and delivers results to your radiologist's worklist within few seconds.

CE-marked

MDR Class IIb

FDA-cleared

Class II

Anterior Circulation Coverage.

Large vessel occlusion is not a single presentation. It spans a spectrum of vessel segments, each carrying a different level of clinical visibility, and a different risk of being missed.

Proximal Occlusion

ICA terminus and MCA M1 occlusions are the most severe presentations of ischemic stroke. When a radiologist identifies one, it triggers an immediate cascade: stroke team activation, angiography suite preparation, thrombectomy team on standby. The call is high-stakes, and it has to be fast. CINA-LVO provides a first-pass analysis before the radiologist opens the scan, so confirmation, not detection, becomes the task.

Distal Occlusion

MCA M2 occlusions are smaller, subtler, and significantly harder to see on CTA. Vessel tortuosity, contrast timing variability, and reading fatigue all raise the risk of a missed finding. Yet M2 occlusions cause real disability, and they are increasingly eligible for mechanical thrombectomy. CINA-LVO is specifically validated on M2, covering the vessel segment where the diagnostic challenge is greatest.

Every CT angiography scan is analyzed automatically, from ICA to MCA, regardless of the time of day, the scan volume, or the complexity of the presentation. The radiologist receives an alert before reviewing the case.

Large Vessel Occlusion Detection

Triage tool for CT angiography detecting large vessel occlusions across the anterior circulation in acute ischemic stroke.

97.9%

Sensitivity

97.6%

Specificity

97.7%

Accuracy

Detection Coverage

ICA MCA M1 MCA M2 Proximal M2

Triage tool for CT angiography detecting large vessel occlusions across the anterior circulation in acute ischemic stroke.

Detection Coverage

ICA MCA M1 MCA M2 Proximal M2

Clinical Evidence

Peer-reviewed studies validating CINA-LVO performance.

2021

Mc Louth et Al.

Frontiers

Validated study across 378 CT angiography scans in an US multicenter, establishing CINA-LVO as a reliable triage tool for acute ischemic stroke across a diverse clinical population.

98.1%

Sensitivity

2023

Temmen et al

Scientific Reports

In a real-world emergency stroke workflow, AI-supported LVO detection reduced average radiologist reading time, a 6.5x acceleration, without loss of diagnostic accuracy.

6.5x faster

Reading Time Reduction

2025

Franciosini et al.

Stroke Journal

In a study of 557 patients specifically including MCA M2 occlusions, confirming CINA-LVO detection accuracy in the vessel segment most often missed on standard CTA review.

93.8%

Sensitivity incl. M2

A Radiologist's Perspective

“When dealing with a stroke, time is of the essence, and being able to prioritize effectively is critical to saving lives and improving outcomes. Not only does CINA help radiologists to identify pathologies quickly, but also to highlight those that require the most urgent care.”

Peter chang

Radiologist, UC Irvine School of Medicine (USA)

Frequently Asked Questions

Which vessel segments does CINA-LVO detect?

CINA-LVO detects large vessel occlusions across the anterior circulation: distal Internal Carotid Artery, the middle cerebral artery M1 segment, and the MCA M2 segment.

How does CINA-LVO handle CTA scans with suboptimal contrast timing or acquisition variability?

CINA-LVO has been validated across multicentre, multivendor cohorts, including scans acquired under varying contrast timing conditions and kilovoltage settings. The algorithm is designed for real-world variability, not just ideal acquisitions. False positives attributable to timing artefacts are addressed through the radiologist’s confirmatory review, which remains the final step before any clinical action.

How does CINA-LVO fit into the stroke workflow without adding steps for the radiologist?

CINA-LVO connects to your PACS via standard DICOM. When a brain CTA is acquired, the analysis runs automatically, with no manual trigger and no separate application. The result appears directly in the radiologist’s worklist as an additional overlay image, with a flag if an occlusion is detected. The radiologist confirms or rules out the finding before any clinical decision is made. No extra login, no workflow change.

CINA-LVO, medical images analysis software, a medical device manufactured by Avicenna.AI. This medical device is reserved for health professionals. The performance and outputs of this tool may differ slightly according to the software version and applicable regulations.

This software has been designed and manufactured according to the EN ISO 13485 Quality management system. Read the instructions in the notice carefully before any use.

Instructions for Use are available.
Manufacturer: Avicenna.AI (France).
Medical device Class IIb following the European Regulation on Medical Device (EU) 2017/745.
Medical device Class II following the Code of Federal Regulations of the United States of America 21CFR on Medical Devices.

Download OUR CASE STUDY

Complete the form below to access the CINA-LVO case study.

AI-Powered Large Vessel Occlusion Detection on CT

Large vessel occlusion is responsible for the most severe ischemic strokes. CINA-LVO analyzes brain CT angiography scans automatically and delivers results to your radiologist's worklist within few seconds.

CE-marked

FDA-cleared

Anterior Circulation Coverage.

Proximal Occlusion

Distal Occlusion

Large Vessel Occlusion Detection

Detection Coverage

Detection Coverage

Clinical Evidence

Mc Louth et Al.

Temmen et al

Franciosini et al.

A Radiologist's Perspective

Peter chang

Frequently Asked Questions

Download OUR CASE STUDY

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